Description

Boc-L-Glutamic Acid γ-Allyl Ester is a protected amino acid derivative of significant importance in synthetic organic and peptide chemistry. This compound serves as a crucial building block, offering orthogonal protection for the side-chain carboxylic acid group of glutamic acid, which is essential for the controlled synthesis of complex peptides and peptide mimetics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of glutamic acid with a selectively protected side chain, enabling the synthesis of complex peptides and proteins.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of peptide-based drugs, enzyme inhibitors, and other pharmacologically active molecules targeting various diseases.
• Bioconjugation & Chemical Biology: The allyl ester protecting group allows for selective deprotection under mild, orthogonal conditions, facilitating site-specific labeling and modification of biomolecules.
• Agrochemical Research: Employed in the synthesis of peptide-like compounds with potential applications as herbicides, fungicides, or plant growth regulators.
• Material Science: Can be used as a monomer or precursor for synthesizing specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	Boc-L-Glutamic Acid γ-Allyl Ester
CAS No.	132286-79-4
Molecular Formula	C₁₃H₂₁NO₆
Molecular Weight	287.31 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-glutamic acid 1-allyl ester; Boc-Glu(OAll)-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]pentanedioic acid 5-allyl ester; Boc-L-Glu(OAll); tert-Butyloxycarbonyl-L-glutamic acid γ-allyl ester; N-Boc-L-glutamic acid 5-allyl ester; L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 5-allyl ester
EINECS	Contact for details

Quality Control

Our Boc-L-Glutamic Acid γ-Allyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.