Description

Boc-Asp(Oall)-Oh CAS NO 132286-77-2 is a protected aspartic acid derivative, specifically an N-tert-butoxycarbonyl (Boc) and O-allyl (OAll) ester protected form. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of aspartic acid while preventing unwanted side reactions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, peptide hormones, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the sequential assembly of peptide chains.
• Pharmaceutical Intermediate: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation and Labeling: The allyl ester protecting group allows for selective deprotection under mild conditions, useful for subsequent conjugation with other molecules.
• Chemical Biology Research: Employed in the synthesis of peptide probes, enzyme substrates, and inhibitors for biochemical studies.
• Custom Peptide Service Providers: A staple reagent for CROs and CDMOs offering bespoke peptide synthesis services.
• Academic Research: Fundamental building block in university and institutional labs for exploring peptide structure and function.

Basic Information

Product Name	Boc-Asp(Oall)-Oh
CAS No.	132286-77-2
Molecular Formula	C₁₂H₁₉NO₆
Molecular Weight	273.28 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-aspartic acid β-allyl ester; Boc-L-Aspartic acid 4-allyl ester; Boc-Asp-OAll; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]butanedioic acid 4-prop-2-enyl ester; Boc-Asp(OAll)-OH; N-Boc-L-aspartic acid β-allyl ester; tert-Butyloxycarbonyl-L-aspartic acid β-allyl ester; L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(2-propen-1-yl) ester
EINECS	Contact for details

Quality Control

Our Boc-Asp(Oall)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive applications like pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation analysis. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation [α]²⁰D	-15.0° to -18.0° (c=1 in DMF)
Chemical Purity (TLC)	Single spot
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.