Description

1,2-Cyclopropanedicarboxylicacid,1-Amino-,cis-(9Ci) is a high-purity, cis-configured cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique strained-ring structure and bifunctional nature make it a valuable precursor for constructing complex molecular architectures with high stereochemical control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel APIs, including potential antiviral, anticancer, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its rigid cyclopropane scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The cyclopropane ring is employed as a rigid, non-hydrolyzable scaffold in the design of peptide mimics and bioisosteric replacements.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylicacid,1-Amino-,cis-(9Ci)
CAS No.	132245-71-7
Molecular Formula	C5H7NO4
Molecular Weight	145.11 g/mol
Synonyms	cis-1-Amino-1,2-cyclopropanedicarboxylic acid; (1R,2S)-1-Aminocyclopropane-1,2-dicarboxylic acid; (1S,2R)-1-Aminocyclopropane-1,2-dicarboxylic acid; ACPD; cis-ACPD; 1-Amino-1,2-cyclopropanedicarboxylic acid, cis-; 1-Aminocyclopropane-1,2-dicarboxylic acid, cis-; 132245-71-7
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarboxylicacid,1-Amino-,cis-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.