Description

(6Ar)-1-(4-Biphenylylmethoxy)-6Aβ,7,10,10Aα-Tetrahydro-6,6,9-Trimethyl-3-Pentyl-6H-Dibenzo[B,D]Pyran CAS NO 132213-91-3 is a high-purity synthetic cannabinoid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical reference standard and key intermediate for the synthesis of novel therapeutic agents targeting the endocannabinoid system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in the production of cannabinoid-based APIs.
• Medicinal Chemistry Research: Serves as a crucial building block or precursor for synthesizing novel cannabinoid receptor agonists and antagonists.
• Preclinical Studies: Employed in in vitro and in vivo studies to investigate pharmacokinetics, metabolism, and receptor binding affinity.
• Analytical Testing: Acts as a certified standard for HPLC, GC-MS, and NMR analysis in forensic and regulatory testing laboratories.
• Biochemical Assay Development: Utilized in high-throughput screening (HTS) to identify and characterize new drug candidates.

Basic Information

Product Name	(6Ar)-1-(4-Biphenylylmethoxy)-6Aβ,7,10,10Aα-Tetrahydro-6,6,9-Trimethyl-3-Pentyl-6H-Dibenzo[B,D]Pyran
CAS No.	132213-91-3
Molecular Formula	C34H40O2
Molecular Weight	480.68 g/mol
Synonyms	JWH-018 N-(4-Biphenylyl) analog; 1-[(1,1'-Biphenyl)-4-ylmethoxy]-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene; Biphenylyl JWH-018; 4-Biphenylyl JWH-018; CP 47,497-C8 homologue (biphenyl variant); Synthetic cannabinoid CP 47,497 C8 homologue biphenyl analog
EINECS	Contact for details

Quality Control

Our (6Ar)-1-(4-Biphenylylmethoxy)-6Aβ,7,10,10Aα-Tetrahydro-6,6,9-Trimethyl-3-Pentyl-6H-Dibenzo[B,D]Pyran is manufactured under strict GMP-like conditions for research use. Every batch undergoes rigorous analytical testing, including HPLC purity assay, identity confirmation (IR, NMR, MS), and residual solvent analysis, to ensure the highest standards of chemical integrity and batch-to-batch consistency. Comprehensive Certificates of Analysis (COA) with full chromatographic data are provided for traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.