Description

(2R,3S)-n-Benzoyl-3-Phenyl Isoserine is a high-purity chiral building block and synthetic intermediate of significant importance in pharmaceutical chemistry. Its defined stereochemistry makes it a critical precursor for the synthesis of complex, biologically active molecules, particularly taxane side chains. This compound is essential for research institutions and manufacturers engaged in the development and production of advanced active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of paclitaxel (Taxol®) and docetaxel side chains.
• API Synthesis: Used in the production of complex, stereospecific active pharmaceutical ingredients requiring the (2R,3S) configuration.
• Fine Chemical Production: Serves as a building block for other high-value specialty chemicals and complex organic molecules.
• Asymmetric Synthesis: Employed in research and development of novel synthetic pathways that rely on its specific stereochemistry.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.
• Academic & Industrial Research: A valuable compound for medicinal chemistry research, process chemistry optimization, and new drug discovery programs.

Basic Information

Item	Detail
Product Name	(2R,3S)-n-Benzoyl-3-Phenyl Isoserine
CAS No.	132201-33-3
Molecular Formula	C16H15NO4
Molecular Weight	285.29 g/mol
Synonyms	(2R,3S)-3-Phenylisoserine N-benzoyl derivative; N-Benzoyl-3-phenylisoserine; (2R,3S)-N-Benzoyl-3-phenylisoserine; β-Phenylisoserine, N-benzoyl-, (2R,3S)-; Taxol Side Chain Intermediate; Docetaxel Side Chain Precursor; (2R-cis)-N-Benzoyl-3-phenylisoserine; (2R,3S)-1-Benzoyl-2-phenyl-3-aminopropane-1,3-diol
EINECS	Contact for details

Quality Control

Our (2R,3S)-n-Benzoyl-3-Phenyl Isoserine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to cGMP principles for pharmaceutical intermediates, and our quality protocols are designed to meet the stringent requirements of our global clientele in the pharmaceutical sector.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.