Description

6-Fluoro-2-Amino-9-(2,3-Dideoxy-β-D-Glycero-Pentofuranosyl)-9H-Purine is a high-purity nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound matters for its critical role in the synthesis of novel antiviral and anticancer agents, offering researchers a precise tool for modifying biological activity. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in the development of next-generation therapeutics, particularly in the fields of virology and oncology. The product is supplied with a guaranteed Certificate of Analysis to ensure research integrity and reproducibility.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside-based antiviral drugs.
• Antiviral Agent Research: Used in the development of experimental compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating purine analogs with potential anticancer activity.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate nucleotide metabolism pathways.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	6-Fluoro-2-Amino-9-(2,3-Dideoxy-β-D-Glycero-Pentofuranosyl)-9H-Purine
CAS No.	132194-21-9
Molecular Formula	C₁₀H₁₂FN₅O₃
Molecular Weight	269.23 g/mol
Synonyms	2-Amino-6-fluoro-9-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-9H-purine; 2-Amino-6-fluoro-9-(2,3-dideoxy-β-D-ribofuranosyl)purine; 6-Fluoro-2-aminopurine 2',3'-dideoxyriboside; 9-(2,3-Dideoxy-β-D-glycero-pentofuranosyl)-2-amino-6-fluoropurine; 2-FA-2',3'-ddR; 2-Amino-6-fluoro-ddPurine; 132194-21-9; 6-F-2-Amino-ddPur
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Amino-9-(2,3-Dideoxy-β-D-Glycero-Pentofuranosyl)-9H-Purine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.