Description

6β-Hydroxy Mometasone Furoate is a key pharmaceutical intermediate and metabolite of the potent corticosteroid mometasone furoate. This compound is of significant value in the research, development, and quality control of anti-inflammatory and anti-allergic medications. It serves as a critical reference standard and building block for analytical laboratories and pharmaceutical manufacturers. Primary users include R&D scientists and QC professionals in the global pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical intermediate for the synthesis of advanced corticosteroid APIs.
• Primary reference standard for the analytical quantification of mometasone furoate and its related substances.
• Metabolite standard for pharmacokinetic and drug metabolism studies.
• Critical raw material in the research and development of new topical and inhaled corticosteroid formulations.
• Used in impurity profiling and stability-indicating methods for mometasone furoate drug products.
• Essential component in the preparation of certified reference materials (CRMs).

Basic Information

Product Name	6β-Hydroxy Mometasone Furoate
CAS No.	132160-74-8
Molecular Formula	C₂₇H₃₀Cl₂O₇
Molecular Weight	537.43 g/mol
Synonyms	6β-Hydroxymometasone Furoate; 6β-Hydroxy Mometasone; 9,21-Dichloro-11β,17-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-6β-yl 2-furoate; Mometasone Furoate 6β-Hydroxy Impurity; Mometasone Furoate Related Compound B; 6β-Hydroxy Mometasone 17-(2-Furoate); 6β-Hydroxy Mometasone 17-Furoate
EINECS	Contact for details

Quality Control

Our 6β-Hydroxy Mometasone Furoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and conformity to stringent specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all test results. Our quality commitment aligns with cGMP principles to support our clients' pharmaceutical development and regulatory submission needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and purity. Handle with appropriate personal protective equipment in a well-ventilated laboratory setting.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.