Description

2-Phenyl-Tetrahydro-2H-Pyran-4-Ol is a versatile chiral building block and intermediate in organic synthesis. This compound is valued for its unique pyran ring structure substituted with a phenyl group and a hydroxyl group, which provides distinct reactivity and stereochemical properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including potential active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and insecticides where its structural motif can contribute to biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric catalysis, such as in hydrogenation or oxidation reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic chemistry, including ring-opening reactions and functional group transformations.

Basic Information

Product Name	2-Phenyl-Tetrahydro-2H-Pyran-4-Ol
CAS No.	132149-01-0
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	2-Phenyltetrahydro-2H-pyran-4-ol; 4-Hydroxy-2-phenyltetrahydro-2H-pyran; 2-Phenyl-4-hydroxytetrahydropyran; 2-Phenyl-4-tetrahydropyranol; 2-Phenyl-4-hydroxyoxane; 4-Hydroxy-2-phenyloxane; 2-Phenyl-4-ol-tetrahydropyran; 2-Phenyl-4-tetrahydropyranyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Phenyl-Tetrahydro-2H-Pyran-4-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.