Description

2-Acetonyl-9-[3-Deoxy-β-D-Ribouranosyl]Hypoxanthine is a specialized nucleoside analog with significant research and development value. This compound is crucial for its role as a key intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular enzymes. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleoside chemistry and medicinal chemistry. The product, with CAS No. 132121-67-6, is supplied to support high-purity synthesis and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate polymerase mechanisms and inhibition.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, chemical biology, and drug discovery.
• Process Development: Acts as a key material in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-Acetonyl-9-[3-Deoxy-β-D-Ribouranosyl]Hypoxanthine
CAS No.	132121-67-6
Molecular Formula	C₁₅H₁₈N₄O₆
Molecular Weight	350.33 g/mol
Synonyms	9-[(3-Deoxy-β-D-ribofuranosyl)-2-acetonyl]hypoxanthine; 2-Acetonyl-9-(3-deoxy-β-D-ribofuranosyl)hypoxanthine; 3'-Deoxy-2-acetonylinosine analog; 9-(3-Deoxy-β-D-ribofuranosyl)-2-(2-oxopropyl)hypoxanthine; 2-(2-Oxopropyl)-9-(3-deoxy-β-D-ribofuranosyl)-9H-purine-6-ol; Nucleoside analog intermediate; 132121-67-6
EINECS	Contact for details

Quality Control

Our 2-Acetonyl-9-[3-Deoxy-β-D-Ribouranosyl]Hypoxanthine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support its use in regulated environments. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Impurity	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.