Description

2-Furanmethanamine,4-Fluorotetrahydro-N,N,5-Trimethyl-,[2S-(2Alpha,4Beta,5Alpha)]- is a high-purity, stereochemically defined fluorinated furan derivative. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its unique structural features that enable the construction of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. The product, identified by CAS No. 132113-41-8, is supplied under stringent quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

This specialized fluorinated amine serves as a versatile intermediate in several high-value chemical sectors:

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active molecules for crop protection and pest management.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and medicinal chemistry within R&D laboratories.

Basic Information

Product Name	2-Furanmethanamine,4-Fluorotetrahydro-N,N,5-Trimethyl-,[2S-(2Alpha,4Beta,5Alpha)]-
CAS No.	132113-41-8
Molecular Formula	C9H16FNO
Molecular Weight	173.23 g/mol
Synonyms	(2S,4R,5S)-4-Fluoro-2,5-dimethyl-N,N-dimethyltetrahydrofuran-2-carboxamide; 4-Fluoro-N,N,2,5-tetramethyltetrahydrofuran-2-carboxamide; (2S,4R,5S)-4-Fluoro-N,N,2,5-tetramethyltetrahydrofuran-2-carboxamide; Fluorinated tetramethylfuran carboxamide; (2α,4β,5α)-4-Fluorotetrahydro-N,N,5-trimethyl-2-furanmethanamine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.