Description

n-Acetyl (4-Bromomethyl)-Dl-Phenylalanine Methyl Ester is a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing peptide mimetics and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in protease inhibitor and peptide-based therapeutic research.
• Peptidomimetic Synthesis: Used to introduce bromomethyl-substituted phenylalanine derivatives into peptide chains, creating analogs with modified biological activity.
• Chemical Biology Probes: Serves as a precursor for labeling reagents or activity-based probes used to study enzyme function and protein interactions.
• Agrochemical Research: Employed in the development of new active ingredients, leveraging its halogenated side chain for further functionalization.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and bioorganic chemistry.
• Custom Synthesis Starting Material: Provides a handle for further cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse chemical libraries.

Basic Information

Product Name	n-Acetyl (4-Bromomethyl)-Dl-Phenylalanine Methyl Ester
CAS No.	132067-39-1
Molecular Formula	C₁₃H₁₆BrNO₃
Molecular Weight	314.18 g/mol
Synonyms	N-Acetyl-4-(bromomethyl)-DL-phenylalanine methyl ester; Methyl N-acetyl-4-(bromomethyl)-DL-phenylalaninate; Ac-(4-BrCH2)-DL-Phe-OMe; DL-N-Acetyl-4-(bromomethyl)phenylalanine methyl ester; (RS)-N-Acetyl-4-(bromomethyl)phenylalanine methyl ester; N-Acetyl-α-amino-4-(bromomethyl)benzenepropanoic acid methyl ester; 4-(Bromomethyl)-N-acetyl-DL-phenylalanine methyl ester
EINECS	Contact for details

Quality Control

Our n-Acetyl (4-Bromomethyl)-Dl-Phenylalanine Methyl Ester is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.