Description

4-Isoxazolecarboxylicacid,5-Amino-3-(Difluoromethyl)-,Methylester(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound, identified by CAS number 132066-24-1, is valued for its unique molecular scaffold that incorporates amino, difluoromethyl, and ester functionalities. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a core structure for developing new-generation fungicides and herbicides with enhanced efficacy and environmental profiles.
• Chemical Biology Probe: Used in medicinal chemistry to explore structure-activity relationships (SAR) and develop enzyme inhibitors.
• Advanced Material Synthesis: A building block for creating specialized polymers and ligands with tailored electronic or binding properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	4-Isoxazolecarboxylicacid,5-Amino-3-(Difluoromethyl)-,Methylester(9Ci)
CAS No.	132066-24-1
Molecular Formula	C6H6F2N2O3
Molecular Weight	192.12 g/mol
Synonyms	5-Amino-3-(difluoromethyl)-4-isoxazolecarboxylic acid methyl ester; Methyl 5-amino-3-(difluoromethyl)-1,2-oxazole-4-carboxylate; 3-(Difluoromethyl)-5-amino-4-isoxazolecarboxylic acid methyl ester; 132066-24-1; 5-Amino-3-difluoromethyl-isoxazole-4-carboxylic acid methyl ester; 4-Isoxazolecarboxylic acid, 5-amino-3-(difluoromethyl)-, methyl ester (9CI)
EINECS	Contact for details

Quality Control

Our production of 4-Isoxazolecarboxylicacid,5-Amino-3-(Difluoromethyl)-,Methylester(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.