Description

9-[(2R,6R)-6-(Hydroxymethyl)-1,4-Oxathian-2-Yl]-3H-Purin-6-One CAS NO 132062-70-5 is a high-purity nucleoside analog with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate. Its primary value lies in its role as a key building block for the synthesis of novel antiviral and anticancer agents, where precise molecular structure is paramount for biological activity. This compound is essential for research institutions and pharmaceutical manufacturers engaged in the development of next-generation therapeutics, particularly within antiviral and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex nucleoside-based active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used as a precursor in the development of novel antiviral compounds targeting specific viral polymerases.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleoside metabolism pathways.
• Process Development: Utilized by process chemistry teams to scale up and optimize synthetic routes for commercial API production.
• Reference Standard: Sourced for use as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	9-[(2R,6R)-6-(Hydroxymethyl)-1,4-Oxathian-2-Yl]-3H-Purin-6-One
CAS No.	132062-70-5
Molecular Formula	C11H14N4O3S
Molecular Weight	282.32 g/mol
Synonyms	(2R,6R)-6-(Hydroxymethyl)-2-(6-oxo-1H-purin-9-yl)-1,4-oxathiane; 9-[(2R,6R)-6-(Hydroxymethyl)-1,4-oxathian-2-yl]-9H-purin-6-ol; 6-Hydroxy-9-[(2R,6R)-6-(hydroxymethyl)-1,4-oxathian-2-yl]purine; 6-Oxo-9-[(2R,6R)-6-(hydroxymethyl)-1,4-oxathian-2-yl]-1H-purine; (2R,6R)-6-(Hydroxymethyl)-2-(6-oxo-1,6-dihydro-9H-purin-9-yl)-1,4-oxathiane; Nucleoside Oxathiane Derivative; Chiral Purine Oxathiane
EINECS	Contact for details

Quality Control

Our 9-[(2R,6R)-6-(Hydroxymethyl)-1,4-Oxathian-2-Yl]-3H-Purin-6-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under conditions of low humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (2R,6R isomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.