Description

3(2H)-Isoxazolone,5-(3-Piperidinyl)-,(R)-(9Ci) is a high-purity, chiral isoxazolone derivative with a defined stereochemistry. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block for the synthesis of complex bioactive molecules. It is essential for research and development teams in the pharmaceutical and agrochemical sectors, particularly those focused on creating novel therapeutics and crop protection agents with specific stereochemical requirements. The product is supplied under stringent quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used as a building block for developing novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the construction of focused libraries for high-throughput screening.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: The piperidinyl-isoxazolone structure can be utilized to develop novel chiral ligands or organocatalysts for asymmetric transformations.
• Academic & Institutional Research: Serves as a reference standard and a starting material for synthetic methodology development in organic and heterocyclic chemistry.

Basic Information

Product Name	3(2H)-Isoxazolone,5-(3-Piperidinyl)-,(R)-(9Ci)
CAS No.	132033-94-4
Molecular Formula	C8H12N2O2
Molecular Weight	168.20 g/mol
Synonyms	(R)-5-(Piperidin-3-yl)-3H-isoxazol-3-one; (R)-5-(3-Piperidinyl)-3(2H)-isoxazolone; 5-(3-Piperidinyl)-3(2H)-isoxazolone, (R)-; (R)-5-(3-Piperidyl)-2H-isoxazol-3-one; 132033-94-4; (R)-enantiomer of 5-(3-Piperidinyl)isoxazol-3(2H)-one
EINECS	Contact for details

Quality Control

Our 3(2H)-Isoxazolone,5-(3-Piperidinyl)-,(R)-(9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR, and mass spectrometry for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.