Description

(2R,3S)-3-Phenylisoserine Methyl Ester is a high-purity, non-natural amino acid derivative and a critical chiral building block in organic synthesis. Its precise stereochemistry makes it an invaluable intermediate for the production of complex pharmaceutical compounds and fine chemicals. This product is essential for research and manufacturing in the pharmaceutical, biotechnology, and advanced material sectors, where strict enantiomeric purity is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly for oncology and antiviral therapies.
• Peptide Synthesis: Used as a protected amino acid derivative in the solid-phase and solution-phase synthesis of novel peptides and peptidomimetics.
• Catalyst & Ligand Development: Serves as a precursor for chiral catalysts and ligands used in asymmetric synthesis.
• Academic & Industrial Research: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high enantiomeric excess.

Basic Information

Product Name	(2R,3S)-3-Phenylisoserine Methyl Ester
CAS No.	131968-74-6
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	Methyl (2R,3S)-3-Phenylisoserinate; (2R,3S)-3-Phenylisoserine Methyl Ester; (2R,3S)-Methyl 3-amino-2-hydroxy-3-phenylpropanoate; (2R,3S)-3-Amino-2-hydroxy-3-phenylpropionic acid methyl ester; (2R,3S)-AHPPA Methyl Ester; Taxol Side Chain Derivative; NSC 330836
EINECS	Contact for details

Quality Control

Our (2R,3S)-3-Phenylisoserine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.