Description

α-((2-(Dimethylamino)Ethoxy)Methyl)-6-Quinolinemethanol (E)-2-Butenedioate (Salt) is a high-purity, complex organic salt with significant potential in advanced pharmaceutical research and development. Its unique molecular structure, featuring a quinoline core linked to a dimethylaminoethoxy moiety, makes it a valuable intermediate for synthesizing novel therapeutic agents. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) research.
• Chemical Biology Probe: Used in research to study enzyme interactions, receptor binding, and other biological pathways due to its specific structural features.
• Process Chemistry Development: Serves as a critical intermediate for scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory synthetic chemistry and medicinal chemistry programs.
• Preclinical Development: Integral component in the early-stage development of new molecular entities before clinical trials.

Basic Information

Product Name	α-((2-(Dimethylamino)Ethoxy)Methyl)-6-Quinolinemethanol (E)-2-Butenedioate (Salt)
CAS No.	131964-35-7
Molecular Formula	C19H26N2O4 • C4H4O4
Molecular Weight	Contact for details
Synonyms	6-Quinolinemethanol, α-[(2-(dimethylamino)ethoxy)methyl]-, (2Z)-2-butenedioate (1:1); (E)-2-Butenedioic acid compound with α-[(2-(dimethylamino)ethoxy)methyl]-6-quinolinemethanol (1:1); Fumarate salt of α-[(2-(dimethylamino)ethoxy)methyl]-6-quinolinemethanol; NSC 697471; Tariquidar fumarate analog intermediate; XR9576 intermediate; P-glycoprotein inhibitor intermediate
EINECS	Contact for details

Quality Control

Our α-((2-(Dimethylamino)Ethoxy)Methyl)-6-Quinolinemethanol (E)-2-Butenedioate (Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.