Description

α-((2-(Dimethylamino)Ethoxy)Methyl)-2'-Methyl-(1,1'-Biphenyl)-4-Methanol Hydrochloride is a high-purity, non-racemic chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its critical role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of novel drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of complex Active Pharmaceutical Ingredients (APIs) and investigational new drugs.
• Asymmetric Synthesis: Used in stereoselective reactions to construct molecules with specific three-dimensional configurations essential for biological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold in drug discovery programs for modifying pharmacophores and optimizing drug-like properties.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for potential commercial pharmaceutical manufacturing.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Acts as a precursor for other high-value, specialized organic compounds used in advanced material science.

Basic Information

Item	Details
Product Name	α-((2-(Dimethylamino)Ethoxy)Methyl)-2'-Methyl-(1,1'-Biphenyl)-4-Methanol Hydrochloride
CAS No.	131961-71-2
Molecular Formula	C21H30ClNO2
Molecular Weight	363.92 g/mol
Synonyms	2'-Methyl-[1,1'-biphenyl]-4-methanol, α-[(2-(dimethylamino)ethoxy)methyl]-, hydrochloride; (R/S)-α-[(2-(Dimethylamino)ethoxy)methyl]-2'-methyl[1,1'-biphenyl]-4-methanol hydrochloride; Biphenylmethanol derivative hydrochloride; DMAM-Biphenyl-MeOH HCl; (α-(2-(Dimethylamino)ethoxy)methyl)-2'-methylbiphenyl-4-methanol HCl; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our α-((2-(Dimethylamino)Ethoxy)Methyl)-2'-Methyl-(1,1'-Biphenyl)-4-Methanol Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.