Description

α-((2-(Dimethylamino)Ethoxy)Methyl)-3-Phenoxybenzenemethanol Hydro Chloride is a high-purity, synthetically derived organic compound primarily utilized as a key pharmaceutical intermediate. Its molecular structure, featuring a phenoxybenzene core with dimethylaminoethoxy and hydroxymethyl substituents, makes it a valuable building block for the synthesis of more complex active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for advanced drug discovery and production processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug research.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral building block for constructing complex API molecules with specific biological activity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable, cost-effective manufacturing routes for target molecules.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.
• Fine Chemical Synthesis: Utilized in the preparation of specialty chemicals and advanced materials requiring its specific structural motif.

Basic Information

Product Name	α-((2-(Dimethylamino)Ethoxy)Methyl)-3-Phenoxybenzenemethanol Hydro Chloride
CAS No.	131961-59-6
Molecular Formula	C19H26ClNO3
Molecular Weight	351.87 g/mol
Synonyms	3-Phenoxy-α-[(2-(dimethylamino)ethoxy)methyl]benzenemethanol hydrochloride; (RS)-α-[(2-(Dimethylamino)ethoxy)methyl]-3-phenoxybenzyl alcohol hydrochloride; 1-[3-Phenoxyphenyl]-2-[(2-dimethylaminoethoxy)]ethanol hydrochloride; Benzenemethanol, α-[(2-(dimethylamino)ethoxy)methyl]-3-phenoxy-, hydrochloride; A-Desmethyl Venlafaxine Hydrochloride; O-Desmethylvenlafaxine Hydrochloride
EINECS	Contact for details

Quality Control

Our α-((2-(Dimethylamino)Ethoxy)Methyl)-3-Phenoxybenzenemethanol Hydro Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identification by spectroscopic methods, to ensure it meets exacting standards for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.