Description

n-Cyclopropylmethyl-3,11C-Ethano-10-Methoxy-1,2,3,3A,11B,11C-Hexahydroaporphine CAS NO 131927-74-7 is a complex, high-purity aporphine alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced pharmaceutical intermediate for synthesizing novel therapeutic agents targeting the central nervous system. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation neuropharmacological treatments.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel aporphine-based drug candidates.
• Neurological Research: Used in preclinical studies to investigate compounds with potential activity on dopamine and other neurotransmitter receptors.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize pharmacological profiles.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Process Chemistry Development: Utilized in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Academic Research: Fundamental studies in alkaloid chemistry and the synthesis of complex heterocyclic compounds.

Basic Information

Product Name	n-Cyclopropylmethyl-3,11C-Ethano-10-Methoxy-1,2,3,3A,11B,11C-Hexahydroaporphine
CAS No.	131927-74-7
Molecular Formula	C23H27NO2
Molecular Weight	349.47 g/mol
Synonyms	10-Methoxy-N-cyclopropylmethyl-3,11C-ethano-1,2,3,3a,11b,11c-hexahydroaporphine; N-Cyclopropylmethyl-10-methoxy-3,11C-ethano-1,2,3,3a,11b,11c-hexahydroaporphine; 10-Methoxy-N-cyclopropylmethyl-3,11-ethanoaporphine; Aporphine derivative 131927-74-7; N-Cyclopropylmethylnorapomorphine ethano-bridged analog; 1,2,9,10-Tetramethoxyaporphine cyclopropylmethyl derivative (related structural analog)
EINECS	Contact for details

Quality Control

Our n-Cyclopropylmethyl-3,11C-Ethano-10-Methoxy-1,2,3,3A,11B,11C-Hexahydroaporphine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting full compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.