Description

Des(Trifluoroethyl) Lansoprazole Sulfide is a key pharmaceutical intermediate in the synthesis of proton pump inhibitors. This compound matters for its critical role in developing advanced active pharmaceutical ingredients (APIs) with enhanced stability and efficacy profiles. It is primarily needed by pharmaceutical R&D laboratories and manufacturers specializing in gastroenterological therapeutics and novel drug development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Lansoprazole and related proton pump inhibitor APIs.
• Research & Development: Used in medicinal chemistry for the development and optimization of new anti-ulcerative and gastroesophageal reflux disease (GERD) treatments.
• Process Chemistry: Employed in scale-up and process optimization studies for the commercial manufacturing of finished dosage forms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and impurity profiling in pharmaceutical production.
• Chemical Synthesis: Utilized in organic synthesis for introducing specific structural motifs into more complex molecules.

Basic Information

Product Name	Des(Trifluoroethyl) Lansoprazole Sulfide
CAS No.	131926-97-1
Molecular Formula	C15H13F3N3O2S
Molecular Weight	356.34 g/mol
Synonyms	2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sulfide; Lansoprazole Sulfide Derivative; Des-Trifluoroethyl Lansoprazole Sulfide; AG-1749 Sulfide Intermediate; (RS)-2-([(3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl]sulfanyl)-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our Des(Trifluoroethyl) Lansoprazole Sulfide is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for pharmaceutical R&D and intermediate use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.