Description

4H-1-Benzopyran-4-One, 6-Fluoro-2-(2-Methyl-2H-1,2,3-Triazol-4-Yl)- is a high-value fluorinated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, combining a benzopyranone core with a fluorinated triazole moiety, makes it an essential building block for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom and triazole ring enhance bioactivity and environmental stability.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its rigid, conjugated structure.
• Chemical Biology Probe: Employed in medicinal chemistry to create fluorescent tags or molecular probes for studying enzyme interactions and cellular pathways.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and fluorine chemistry.

Basic Information

Product Name	4H-1-Benzopyran-4-One, 6-Fluoro-2-(2-Methyl-2H-1,2,3-Triazol-4-Yl)-
CAS No.	131924-40-8
Molecular Formula	C₁₂H₈FN₃O₂
Molecular Weight	245.21 g/mol
Synonyms	6-Fluoro-2-(2-methyl-2H-1,2,3-triazol-4-yl)-4H-chromen-4-one; 6-Fluoro-2-(2-methyl-2H-1,2,3-triazol-4-yl)chromone; 6-Fluoro-2-(2-methyl-2H-[1,2,3]triazol-4-yl)-4H-chromen-4-one; 131924-40-8; Chromone, 6-fluoro-2-(2-methyl-2H-1,2,3-triazol-4-yl)-; 4H-1-Benzopyran-4-one, 6-fluoro-2-(2-methyl-2H-1,2,3-triazol-4-yl)-; 6-Fluoro-2-(2-methyl-2H-1,2,3-triazol-4-yl)-4H-1-benzopyran-4-one
EINECS	Contact for details

Quality Control

Our production of 4H-1-Benzopyran-4-One, 6-Fluoro-2-(2-Methyl-2H-1,2,3-Triazol-4-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP compliance for pharmaceutical applications, and we welcome audits and specific quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture absorption. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.