Description

(11β,16α)-21-(Acetyloxy)-11,16,17-Trihydroxypregna-1,4,14-Triene-3,20-Dione is a high-purity synthetic steroid derivative with significant research and pharmaceutical development potential. This compound is valued for its precise molecular structure, which serves as a critical intermediate or reference standard in advanced organic synthesis and medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.
• Biochemical Research: Employed in in vitro studies to investigate steroid receptor interactions, metabolic pathways, and biological activity profiles.
• Process Development: Acts as a critical material for scaling up and optimizing synthetic routes in process chemistry within GMP environments.

Basic Information

Product Name	(11β,16α)-21-(Acetyloxy)-11,16,17-Trihydroxypregna-1,4,14-Triene-3,20-Dione
CAS No.	131918-72-4
Molecular Formula	C23H28O7
Molecular Weight	416.47 g/mol
Synonyms	21-Acetoxy-11β,16α,17-trihydroxypregna-1,4,14-triene-3,20-dione; 11β,16α,17,21-Tetrahydroxypregna-1,4,14-triene-3,20-dione 21-acetate; 21-O-Acetyl-11β,16α,17-trihydroxypregna-1,4,14-triene-3,20-dione; 11β,16α,17-Trihydroxy-21-(acetyloxy)pregna-1,4,14-triene-3,20-dione; 11β,16α,17-Trihydroxypregna-1,4,14-triene-3,20-dione 21-acetate; A Steroid D-ring Lactone Derivative; Prednisolone derivative intermediate.
EINECS	Contact for details

Quality Control

Our production of (11β,16α)-21-(Acetyloxy)-11,16,17-Trihydroxypregna-1,4,14-Triene-3,20-Dione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.