Description

(3R)-(+)-3-Acetamidopyrrolidine CAS NO 131900-62-4 is a high-purity, chiral pyrrolidine derivative featuring an acetamide functional group. This compound serves as a critical chiral building block and intermediate in the synthesis of complex, biologically active molecules. It is essential for research and development in the pharmaceutical industry, particularly for medicinal chemists and process development scientists working on new drug candidates, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective chemical reactions to introduce the (3R) configuration.
• Medicinal Chemistry Research: Employed in the design and synthesis of compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for drug candidates.
• Biochemical Tool: Can be utilized in the development of enzyme inhibitors or probes for studying biological pathways.
• Fine Chemical Synthesis: A valuable building block for creating complex, high-value specialty chemicals beyond pharmaceuticals.

Basic Information

Product Name	(3R)-(+)-3-Acetamidopyrrolidine
CAS No.	131900-62-4
Molecular Formula	C6H12N2O
Molecular Weight	128.17 g/mol
Synonyms	(R)-(+)-3-Acetamidopyrrolidine; (3R)-3-Acetamidopyrrolidine; (+)-3-Acetamidopyrrolidine; (R)-3-Acetamidopyrrolidine; 1-(3R)-3-Pyrrolidinylacetamide; (R)-1-(3-Pyrrolidinyl)acetamide; (3R)-3-Acetamido-1-azacyclopentane
EINECS	Contact for details

Quality Control

Our (3R)-(+)-3-Acetamidopyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.