Description

(S)-(-)-1-Benzyl-3-(Boc-Amino)Pyrrolidine CAS NO 131852-53-4 is a high-purity chiral intermediate of significant importance in modern asymmetric synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Used as a versatile chiral auxiliary or precursor in stereoselective reactions to introduce the (S)-pyrrolidine scaffold.
• Peptidomimetics Research: Serves as a constrained proline analog for constructing peptidomimetic libraries in medicinal chemistry for drug discovery programs.
• Catalyst Ligand Precursor: Acts as a starting material for the synthesis of chiral ligands used in homogeneous catalysis, such as asymmetric hydrogenation.
• Agrochemical Synthesis: Employed in the research and development of advanced, enantiomerically pure agrochemicals.
• Academic & R&D: Essential for methodological development in organic chemistry and for exploring new synthetic pathways in university and institutional laboratories.

Basic Information

Product Name	(S)-(-)-1-Benzyl-3-(Boc-Amino)Pyrrolidine
CAS No.	131852-53-4
Molecular Formula	C17H26N2O2
Molecular Weight	290.40 g/mol
Synonyms	(S)-1-Benzyl-3-((tert-butoxycarbonyl)amino)pyrrolidine; (S)-N-Boc-3-Amino-1-benzylpyrrolidine; (S)-3-[(tert-Butoxycarbonyl)amino]-1-benzylpyrrolidine; tert-Butyl (S)-1-benzylpyrrolidin-3-ylcarbamate; (S)-1-Benzyl-3-(Boc-amino)pyrrolidine; (S)-N-Boc-1-benzyl-3-aminopyrrolidine; (S)-1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine; (3S)-1-Benzyl-3-[[(2-methylpropan-2-yl)oxycarbonyl]amino]pyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-(-)-1-Benzyl-3-(Boc-Amino)Pyrrolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.