Description

(S)-3-Amino-3-(2-Thienyl)-Propionic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a chiral center and a thiophene moiety. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical agents and bioactive molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereochemistry and heterocyclic functionality into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in neurology and metabolic disease research.
• Peptidomimetics & Drug Discovery: Used to incorporate the thienylalanine analog into peptide backbones to modulate biological activity, stability, and receptor binding.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, or plant growth regulators with specific chiral activity.
• Biochemical Research: Utilized in enzymatic studies and as a substrate analog to investigate metabolic pathways and enzyme mechanisms.
• Ligand & Catalyst Development: The amino and carboxylic acid functional groups make it suitable for designing novel chelating ligands and organocatalysts.

Basic Information

Item	Details
Product Name	(S)-3-Amino-3-(2-Thienyl)-Propionic Acid
CAS No.	131829-50-0
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	(S)-3-Amino-3-(thiophen-2-yl)propanoic acid; (S)-β-Amino-β-(2-thienyl)propionic acid; (S)-2-Thienylalanine; (S)-3-Amino-3-(2-thienyl)propanoic acid; (S)-3-(2-Thienyl)-β-alanine; (S)-3-(Thiophen-2-yl)-β-alanine; (S)-β-(2-Thienyl)alanine; (S)-Tpa-OH
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-3-(2-Thienyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC) and chemical identity confirmation (NMR, IR), to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.