Description

n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl-2-Bromo-n-Methyl-D-Tryptophan is a sophisticated, non-natural amino acid derivative designed for advanced pharmaceutical research and development. This compound serves as a critical building block (synthon) in the synthesis of complex peptides and peptidomimetics, enabling the exploration of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and contract research organizations (CROs) focused on oncology, metabolic disorders, and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of bioactive peptides and peptidomimetic drug candidates.
• Protease Inhibitor Development: Used to construct specialized amino acid residues for inhibitors targeting specific enzymes like proteases.
• Chemical Biology Research: Employed in the study of protein-protein interactions and signal transduction pathways using modified peptide probes.
• Anticancer Agent Synthesis: Incorporated into peptide-based constructs designed for targeted cancer therapies.
• Peptide Library Construction: Serves as a unique, brominated tryptophan analog for creating diverse screening libraries in drug discovery.
• Academic Research: Used in university and institutional labs for fundamental studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl-2-Bromo-n-Methyl-D-Tryptophan
CAS No.	131791-79-2
Molecular Formula	C20H26BrN3O5
Molecular Weight	468.34 g/mol
Synonyms	Boc-L-Ala-2-Br-N-Me-D-Trp-OH; Boc-L-Alanyl-2-bromo-N-methyl-D-tryptophan; (2R)-2-[[(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-3-(2-bromo-1-methyl-1H-indol-3-yl)propanoic acid; 2-Bromo-N-methyl-D-tryptophan Boc-L-alanine; N-Boc-L-alanyl-2-bromo-N-methyl-D-tryptophan; N-(tert-Butoxycarbonyl)-L-alanyl-2-bromo-N-methyl-D-tryptophan; Boc-Ala-2-Br-N-Me-D-Trp; L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-, (2R)-2-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]-3-(2-bromo-1-methyl-1H-indol-3-yl)-
EINECS	Contact for details

Quality Control

Our n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl-2-Bromo-n-Methyl-D-Tryptophan is manufactured under strict quality systems suitable for research and development use. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for advanced pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. The compound is moisture-sensitive; keep the container tightly sealed in a dry place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.