Description

2,3,4,6-Tetra-o-Benzyl-5-Thio-D-Glucono-1,5-Lactone is a sophisticated, protected thioglyconolactone derivative, a key chiral building block in organic synthesis. This compound matters for its role as a crucial intermediate in the synthesis of complex carbohydrates, nucleosides, and other biologically active molecules, enabling precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in antiviral and anticancer research.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel nucleoside analogs and carbohydrate-based drugs.
• Glycochemistry Research: Used in the preparation of thioglycosides and other modified sugars for studying carbohydrate-protein interactions.
• Antiviral Drug Development: Serves as a building block for potential antiviral agents targeting viral replication mechanisms.
• Chemical Biology Probes: Employed in the creation of labeled or tagged sugar derivatives for metabolic pathway studies.
• Process Chemistry: Utilized in scale-up routes for the production of active pharmaceutical ingredients (APIs) requiring specific sugar modifications.
• Academic & Industrial R&D: A valuable reagent for methodological development in stereoselective synthesis and medicinal chemistry.

Basic Information

Product Name	2,3,4,6-Tetra-o-Benzyl-5-Thio-D-Glucono-1,5-Lactone
CAS No.	131757-92-1
Molecular Formula	C34H34O5S
Molecular Weight	554.70 g/mol
Synonyms	5-Thio-2,3,4,6-tetra-O-benzyl-D-glucono-1,5-lactone; Tetra-O-benzyl-5-thio-D-glucono-1,5-lactone; 2,3,4,6-Tetra-O-benzyl-5-thio-D-gluconolactone; 5-Thio-D-glucono-1,5-lactone 2,3,4,6-tetrabenzyl ether; D-Glucono-1,5-lactone, 5-thio-, 2,3,4,6-tetrakis-O-(phenylmethyl)-; Protected 5-Thioglucuronolactone
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Benzyl-5-Thio-D-Glucono-1,5-Lactone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.