Description

(R)-3-Amino-3-(4-Chloro-Phenyl)-Propionic Acid CAS NO 131690-61-4 is a high-purity, non-natural chiral amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a key chiral intermediate for the development of novel pharmaceuticals and bioactive compounds, enabling precise stereochemical control. This product is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs, enzyme inhibitors, and other therapeutic agents.
• Agrochemical Research: Used in the design and synthesis of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Peptidomimetics & Drug Discovery: Incorporated into peptide analogs and peptidomimetics to enhance metabolic stability, bioavailability, and target specificity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals where stereochemical integrity is paramount.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate biological pathways and mechanisms.

Basic Information

Item	Details
Product Name	(R)-3-Amino-3-(4-Chloro-Phenyl)-Propionic Acid
CAS No.	131690-61-4
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	(R)-3-Amino-3-(4-chlorophenyl)propanoic acid; (R)-3-Amino-3-(p-chlorophenyl)propionic acid; (R)-4-Chloro-β-phenyl-β-alanine; D-3-Amino-3-(4-chlorophenyl)propionic acid; (R)-β-Amino-4-chlorohydrocinnamic acid; (3R)-3-Amino-3-(4-chlorophenyl)propanoic acid; (R)-3-(4-Chlorophenyl)-3-aminopropionic acid
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-(4-Chloro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) documenting identity, purity, chiral purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.