Description

(S)-3-Amino-2-Benzylpropanoic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a benzyl side chain. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly peptidomimetics and enzyme inhibitors. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries seeking to introduce specific stereochemistry and functional groups into their target compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in protease inhibitor and cardiovascular drug candidates.
• Peptidomimetic Research: Used to construct peptide analogs with enhanced metabolic stability and bioavailability for drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical reactions to create enantiomerically pure products.
• Bioconjugation & Linker Chemistry: The amino and carboxylic acid functional groups allow for conjugation to other molecules, useful in creating drug-linker systems for antibody-drug conjugates (ADCs).
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and protein-protein interactions.
• Fine Chemical Synthesis: A versatile intermediate for synthesizing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	(S)-3-Amino-2-Benzylpropanoic Acid
CAS No.	131683-27-7
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(S)-2-Benzyl-3-aminopropanoic acid; (S)-3-Amino-2-benzylpropionic acid; (S)-β-Amino-β-benzylpropionic acid; (S)-3-Amino-2-phenylmethylpropanoic acid; D-BAPA; (S)-Homo-phenylalanine β-amine; L-2-Benzyl-3-aminopropanoic acid (common naming); (2S)-3-Amino-2-benzylpropanoic acid (IUPAC)
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-2-Benzylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.