Description

Ethyl cis-5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant chiral building block and intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry where its defined stereochemistry is crucial for biological activity. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in creating new active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents.
• API Synthesis: Used in the construction of complex molecular scaffolds for potential drug candidates.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce the cis-5-amino-tetrahydropyran moiety.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.
• Bioconjugate Chemistry: Potential use in the development of targeted drug delivery systems or diagnostic agents.

Basic Information

Product Name	Ethyl cis-5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride
CAS No.	131651-14-4
Molecular Formula	C9H18ClNO3
Molecular Weight	223.70 g/mol
Synonyms	Ethyl (5R,6S)-5-Amino-3,4,5,6-tetrahydro-2H-pyran-2-carboxylate hydrochloride; Ethyl cis-5-Amino-3,4,5,6-tetrahydro-2H-pyran-2-carboxylate HCl; 5-Amino-tetrahydropyran-2-carboxylic acid ethyl ester hydrochloride; cis-5-Amino-tetrahydropyran-2-carboxylic acid ethyl ester hydrochloride; 2H-Pyran-2-carboxylic acid, 5-amino-3,4,5,6-tetrahydro-, ethyl ester, hydrochloride, (5R,6S)-; (5R,6S)-5-Amino-3,4,5,6-tetrahydro-2H-pyran-2-carboxylic Acid Ethyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl cis-5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.