Description

7-Chloro-8-Hydroxy-1-(3'-Iodophenyl)-3-Methyl-2,3,4,5-Tetrahydro-1H-3-Benzazepine is a high-purity, synthetically derived benzazepine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological reference standard and a versatile chemical building block for designing novel therapeutic agents. It is primarily required by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors for applications in neuroscience and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel central nervous system (CNS) active compounds and receptor ligands.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies targeting dopamine and serotonin receptor subtypes.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new drug candidates.
• Process Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in neurochemistry and molecular pharmacology.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	7-Chloro-8-Hydroxy-1-(3'-Iodophenyl)-3-Methyl-2,3,4,5-Tetrahydro-1H-3-Benzazepine
CAS No.	131567-14-1
Molecular Formula	C17H17ClINO
Molecular Weight	413.68 g/mol
Synonyms	1-(3-Iodophenyl)-7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 7-Chloro-8-hydroxy-1-(3-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 131567-14-1; 3-Benzazepine, 7-chloro-8-hydroxy-1-(3-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-; Benzazepine derivative, 7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Hydroxy-1-(3'-Iodophenyl)-3-Methyl-2,3,4,5-Tetrahydro-1H-3-Benzazepine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.