Description

Ethyl 3,4-Di-o-Acetyl-2-Deoxy-2-Phthalimido-1-Thio-β-D-Glucopyranoside is a sophisticated, high-purity thioglycoside building block critical for advanced organic synthesis. This compound matters because it serves as a key chiral intermediate for constructing complex carbohydrate mimetics and glycoconjugates with high stereochemical fidelity. Pharmaceutical and biotechnology R&D teams need it for developing novel therapeutics, including enzyme inhibitors and targeted drug delivery systems, where precise glycosylation is essential.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel glycosidase inhibitors and antiviral agents.
• Glycobiology Research: Used as a protected thioglycoside donor for constructing complex oligosaccharides and glycopeptides in academic and industrial research.
• Carbohydrate Mimetic Synthesis: Enables the production of stable glycomimetics for studying carbohydrate-protein interactions and developing diagnostic tools.
• Chemical Biology Probes: Acts as a building block for creating activity-based probes to study glycosylation enzymes and pathways.
• Process Development: Serves as a reference standard and starting material for scaling up the production of carbohydrate-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Ethyl 3,4-Di-o-Acetyl-2-Deoxy-2-Phthalimido-1-Thio-β-D-Glucopyranoside
CAS No.	131545-00-1
Molecular Formula	C₂₂H₂₅NO₉S
Molecular Weight	479.50 g/mol
Synonyms	Ethyl 2-Deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 3,4-Diacetate; 1-Thioethyl 3,4-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside; Ethyl 1-Thio-β-D-glucopyranoside, 3,4-diacetate 2-deoxy-2-phthalimido derivative; NSC 405122; 2-Deoxy-2-phthalimido-β-D-glucopyranosyl ethyl sulfide 3',4'-diacetate; β-D-Glucopyranoside, ethyl 3,4-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-
EINECS	Contact for details

Quality Control

Our Ethyl 3,4-Di-o-Acetyl-2-Deoxy-2-Phthalimido-1-Thio-β-D-Glucopyranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.