Description

(-)-2-β-Carbomethoxy-3-β-(4-Fluorophenyl)Nortropane is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is a critical precursor in the synthesis of specialized neuropharmacological agents, offering significant value for drug discovery and development programs. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of tropane-based compounds and other neuroactive pharmaceuticals.
• Neurological Research: Used as a reference standard and precursor in studies investigating neurotransmitter transporters, particularly dopamine and serotonin reuptake mechanisms.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs aimed at developing novel CNS-targeting therapeutics.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening assays for pharmacological evaluation.
• Reference Material: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control.
• Academic Synthesis: A valuable compound for advanced organic chemistry research and methodology development in academic settings.

Basic Information

Product Name	(-)-2-β-Carbomethoxy-3-β-(4-Fluorophenyl)Nortropane
CAS No.	131488-15-8
Molecular Formula	C₁₆H₂₀FNO₂
Molecular Weight	277.34 g/mol
Synonyms	(-)-2β-Carbomethoxy-3β-(4-fluorophenyl)nortropane; WIN 35,428; CFT; 2β-Carbomethoxy-3β-(4-fluorophenyl)tropane; (1R,2S,3S,5S)-3-(4-Fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester; β-CFT; Contact for details on additional aliases.
EINECS	Contact for details

Quality Control

Our (-)-2-β-Carbomethoxy-3-β-(4-Fluorophenyl)Nortropane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance with cGMP and research-grade standards for reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.