Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-6-(Methylthio)-, (2-Exo,6-Endo)- (9Ci) is a high-purity, structurally complex bicyclic amino acid derivative with significant synthetic utility. This compound serves as a critical chiral building block and advanced intermediate for the synthesis of novel pharmaceuticals and bioactive molecules. It is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and as a scaffold for designing novel drug candidates with constrained geometries.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis to introduce complex molecular architectures.
• Bioconjugation & Peptidomimetics: Acts as a non-natural amino acid analog for creating modified peptides and bioconjugates with enhanced stability or binding properties.
• Chemical Biology Probes: Utilized in the development of chemical probes to study enzyme function and biological target engagement.
• Agrochemical Research: Potential intermediate for the synthesis of advanced, high-specificity crop protection agents.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-6-(Methylthio)-, (2-Exo,6-Endo)- (9Ci)
CAS No.	131486-46-9
Molecular Formula	C9H15NO2S
Molecular Weight	201.29 g/mol
Synonyms	2-Amino-6-(methylthio)bicyclo[2.2.1]heptane-2-carboxylic acid; (1S,2R,4R)-2-Amino-6-(methylthio)bicyclo[2.2.1]heptane-2-carboxylic acid; (2-Exo,6-Endo)-2-Amino-6-(methylthio)bicyclo[2.2.1]heptane-2-carboxylic acid; 6-(Methylthio)-2-azanorbornane-2-carboxylic acid; Exo-2-Amino-endo-6-(methylthio)bicyclo[2.2.1]heptane-2-carboxylic acid; NSC 339586; A constrained methionine analog
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-6-(Methylthio)-, (2-Exo,6-Endo)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.