Description

3-Cyclopropyl-2,2-Dimethyl-Propionic Acid is a specialized organic acid building block characterized by its unique cyclopropyl and gem-dimethyl substituted structure. This compound is valued for its role as a key chiral intermediate in the synthesis of complex molecules, offering a rigid, sterically defined framework for advanced chemical construction. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	3-Cyclopropyl-2,2-Dimethyl-Propionic Acid
CAS No.	131469-76-6
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	2,2-Dimethyl-3-cyclopropylpropanoic Acid; 3-Cyclopropyl-2,2-dimethylpropanoic Acid; Cyclopropanepropanoic acid, 2,2-dimethyl-; (3-Cyclopropyl-2,2-dimethyl-propionyl)oxy; 2,2-Dimethyl-3-cyclopropyl-propionic Acid; α,α-Dimethylcyclopropanepropionic Acid
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-2,2-Dimethyl-Propionic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.