Description

(2R,3S)-1,1-Dimethyl-2-(3-oxobutyl)-3-(3-cyano-1-methylenepropyl) cyclobutane, 96 is a high-purity, stereochemically defined cyclobutane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique molecular architecture, featuring both ketone and cyano functional groups on a constrained ring system, makes it invaluable for constructing complex, biologically active molecules with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals where stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides, where the specific spatial orientation of the molecule can significantly influence biological activity and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance ingredients, flavors, and other high-value specialty chemicals requiring defined stereocenters.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, enabling exploration of new cyclobutane ring transformations and C-C bond-forming reactions.
• Material Science Research: Potential monomer or cross-linker for developing polymers with tailored thermal and mechanical properties derived from the rigid cyclobutane core.

Basic Information

Item	Details
Product Name	(2R,3S)-1,1-Dimethyl-2-(3-oxobutyl)-3-(3-cyano-1-methylenepropyl) cyclobutane, 96
CAS No.	131468-89-8
Molecular Formula	C15H23NO
Molecular Weight	233.35 g/mol
Synonyms	(2R,3S)-1,1-Dimethyl-2-(3-oxobutyl)-3-(3-cyano-1-methylenepropyl)cyclobutane; (2R,3S)-1,1-Dimethyl-2-(3-oxobutyl)-3-(3-cyano-1-methyl-2-propenyl)cyclobutane; (2R,3S)-3-(3-Cyano-1-methylenepropyl)-1,1-dimethyl-2-(3-oxobutyl)cyclobutane; Chiral Cyclobutane Ketonitrile Derivative; (2R,3S)-Cyclobutane Building Block; CAS 131468-89-8
EINECS	Contact for details

Quality Control

Every batch of our (2R,3S)-1,1-Dimethyl-2-(3-oxobutyl)-3-(3-cyano-1-methylenepropyl) cyclobutane, 96 is manufactured and tested under a strict quality management system. We guarantee the specified chiral purity and chemical identity through comprehensive analytical techniques. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, enantiomeric excess, and impurity profiles to ensure it meets the exacting standards required for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.