Description

2-(Ethoxycarbonyl)Phenylzinc Bromide is a highly reactive organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation through cross-coupling reactions, offering superior functional group tolerance and selectivity compared to other organometallics. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for complex molecule synthesis. CAS No. 131379-40-3.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl motifs prevalent in active pharmaceutical ingredients (APIs) via Negishi, Kumada, or other transition-metal-catalyzed cross-couplings.
• Agrochemical Active Ingredient Development: Used in the synthesis of complex aromatic and heteroaromatic compounds for novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Material Science Research: Employed in the creation of conjugated polymers and organic electronic materials for OLEDs, OFETs, and photovoltaic applications.
• Fine Chemical and Flavor/Fragrance Manufacturing: Facilitates the production of substituted aromatic esters and other specialty aromatic compounds.
• Academic and R&D Laboratories: A valuable tool for methodological development and exploring new synthetic pathways in organic synthesis.

Basic Information

Item	Detail
Product Name	2-(Ethoxycarbonyl)Phenylzinc Bromide
CAS No.	131379-40-3
Molecular Formula	C9H9BrO2Zn
Molecular Weight	294.47 g/mol
Synonyms	(2-Ethoxycarbonylphenyl)zinc bromide; Ethyl 2-(bromozincio)benzoate; 2-Carbethoxyphenylzinc bromide; o-Ethoxycarbonylphenylzinc bromide; Zinc, bromo(2-ethoxycarbonylphenyl)-; Bromo(2-ethoxycarbonylphenyl)zinc; Ethyl 2-bromozinciobenzoate
EINECS	Contact for details

Quality Control

Every batch of 2-(Ethoxycarbonyl)Phenylzinc Bromide is manufactured and tested under strict quality management protocols to ensure consistency and reliability for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by titration), zinc content, and halide content. Our quality systems are designed to support cGMP compliance for pharmaceutical intermediate use, and we can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. This material is moisture-sensitive (hygroscopic) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF)
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Zinc Content	Conforms
Bromide Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.