Description

4-Ethoxy-4-Oxobutylzinc Bromide is a highly reactive organozinc reagent used in organic synthesis. This compound is valued for its role in facilitating key carbon-carbon bond formation reactions, such as Negishi cross-couplings, enabling the construction of complex molecular frameworks. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials.
• Negishi Cross-Coupling Reactions: Serves as a crucial reagent for coupling with various organic electrophiles to form new C-C bonds.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploratory organic synthesis.

Basic Information

Item	Detail
Product Name	4-Ethoxy-4-Oxobutylzinc Bromide
CAS No.	131379-39-0
Molecular Formula	C6H11BrO2Zn
Molecular Weight	260.45 g/mol
Synonyms	Ethyl 4-(Bromozincio)butanoate; 4-(Bromozincio)butanoic Acid Ethyl Ester; Butanoic acid, 4-(bromozincio)-, ethyl ester; Zinc, bromo[4-(ethoxycarbonyl)butyl]-; Bromo(4-ethoxy-4-oxobutyl)zinc
EINECS	Contact for details

Quality Control

Our production of 4-Ethoxy-4-Oxobutylzinc Bromide adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized using advanced analytical techniques, including NMR, titration, and GC/HPLC, to confirm identity, purity, and solution concentration. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), this reagent must be handled and stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (GC/HPLC)	≥ 95% (on solvent-free basis)
Zinc Content	Contact for details
Bromide Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.