Description

2-Cyanophenylzinc Bromide is a versatile organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation through cross-coupling reactions, offering excellent functional group tolerance and selectivity. This compound is particularly essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex aromatic structures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the introduction of the 2-cyanophenyl moiety into target molecules via Negishi, Kumada, or other transition-metal catalyzed cross-couplings.
• Agrochemical Active Ingredient Development: Used in the research and production of herbicides, fungicides, and insecticides that require specific biphenyl or heterocyclic frameworks.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise aromatic architecture is critical.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring aryl-metal coupling steps.

Basic Information

Product Name	2-Cyanophenylzinc Bromide
CAS No.	131379-17-4
Molecular Formula	C7H4BrNZn
Molecular Weight	247.41 g/mol
Synonyms	2-Cyanophenylzinc bromide solution; (2-Cyanophenyl)zinc bromide; Zinc, bromo(2-cyanophenyl)-; Bromo(2-cyanophenyl)zinc; o-Cyanophenylzinc bromide; 2-Cyanobenzenezinc bromide; Bromo(2-cyanophenyl)zinc solution (typical in THF)
EINECS	Contact for details

Quality Control

Our 2-Cyanophenylzinc Bromide is manufactured under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by NMR spectroscopy and titration to confirm identity, concentration, and active reagent content. Certificates of Analysis (COA) detailing exact concentration (typically 0.5M in THF), purity, and residual metal profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For optimal stability, maintain at recommended temperatures between 2°C and 8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (typical)
Assay (Titration)	≥ 95% (as C7H4BrNZn)
Identification (NMR)	Conforms to structure
Water Content (Karl Fischer)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.