Description

4-(Ethoxycarbonyl)Phenylzinc Bromide is a versatile organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation through cross-coupling reactions, offering superior functional group tolerance and stability compared to some other organometallic species. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the Negishi cross-coupling reaction, used to introduce the 4-(ethoxycarbonyl)phenyl moiety into target molecules for active pharmaceutical ingredient (API) development.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators that require specific aryl carboxylic ester functionalities.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and metal-organic frameworks (MOFs) used in catalysis and material science.
• Fine Chemical Manufacturing: Used in the production of specialty chemicals, dyes, and liquid crystals where precise aryl group incorporation is critical.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and for exploring new catalytic cycles in transition metal chemistry.

Basic Information

Product Name	4-(Ethoxycarbonyl)Phenylzinc Bromide
CAS No.	131379-15-2
Molecular Formula	C9H9BrO2Zn
Molecular Weight	294.46 g/mol
Synonyms	(4-Ethoxycarbonylphenyl)zinc bromide; Ethyl 4-(bromozincio)benzoate; Zinc, bromo[4-(ethoxycarbonyl)phenyl]-; p-(Ethoxycarbonyl)phenylzinc bromide; 4-Carbethoxyphenylzinc bromide; Bromo[4-(ethoxycarbonyl)phenyl]zinc; Benzoic acid, 4-(bromozincio)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-(Ethoxycarbonyl)Phenylzinc Bromide is manufactured and tested under strict quality management protocols to ensure consistency and reliability for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by titration), zinc content, and bromide content. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For optimal long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Solution (typically in THF or ether)
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Zinc (Zn) Content	Conforms
Bromide (Br) Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.