Description

4-Cyanophenylzinc Bromide is a versatile organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the Negishi cross-coupling reaction to introduce the 4-cyanophenyl moiety into target molecules, crucial for creating active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by constructing biaryl structures with specific functional groups.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and metal-organic frameworks (MOFs) used in catalysis and material science.
• Functional Material Production: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the cyanophenyl group imparts specific electronic or structural properties.
• Fine Chemical Manufacturing: Facilitates the production of complex, high-value specialty chemicals and dyes through selective aryl-aryl coupling.
• Academic & R&D Laboratories: A fundamental tool for methodological development in organic synthesis and exploring new catalytic cycles.

Basic Information

Product Name	4-Cyanophenylzinc Bromide
CAS No.	131379-14-1
Molecular Formula	C7H4BrNZn
Molecular Weight	247.41 g/mol
Synonyms	(4-Cyanophenyl)zinc bromide; p-Cyanophenylzinc bromide; Zinc, bromo(4-cyanophenyl)-; 4-Cyanophenylzinc bromide solution; (4-Cyanophenyl)zinc bromide solution; Bromo(4-cyanophenyl)zinc; Arylzinc bromide reagent
EINECS	Contact for details

Quality Control

Our 4-Cyanophenylzinc Bromide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes comprehensive analysis, including titration for zinc content and spectroscopic methods for identity and purity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key specifications to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive). For optimal stability and to maintain reactivity, store sealed vials or flasks under an inert gas (argon or nitrogen) at recommended cold temperatures, typically between 2°C and 8°C. Keep the container dry and in a well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (Typical)
Assay (Zn Titration)	≥ 95%
Identification (IR)	Conforms to structure
Purity (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.