Description

5-(Bromomethyl)Benzo[D]Thiazole is a versatile brominated heterocyclic building block of significant synthetic utility. This compound is valued for its role as a key intermediate in the construction of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for applications in medicinal chemistry and functional material synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those containing the benzothiazole pharmacophore, which is associated with a range of biological activities.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, where the benzothiazole moiety can enhance efficacy.
• Material Science Research: Acts as a building block for creating organic ligands, functional polymers, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes and molecular tags for studying biological systems.
• Cross-Coupling Reactions: The bromomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for catalysis or as a core structure for catalyst development.

Basic Information

Product Name	5-(Bromomethyl)Benzo[D]Thiazole
CAS No.	131337-65-0
Molecular Formula	C8H6BrNS
Molecular Weight	228.11 g/mol
Synonyms	5-(Bromomethyl)benzothiazole; 2-(Bromomethyl)benzothiazole (common numbering); Benzo[d]thiazole, 5-(bromomethyl)-; 1,3-Benzothiazole, 5-(bromomethyl)-; 5-Bromomethylbenzothiazole; 5-(Bromomethyl)-1,3-benzothiazole; 2-Bromomethylbenzothiazole (alternative isomer designation)
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)Benzo[D]Thiazole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.