Description

2-Oxetanone,3-Amino-4-Methyl-,(3S-Trans)-(9Ci) CAS NO 131232-74-1 is a high-purity, stereochemically defined chiral building block belonging to the β-lactam class of heterocyclic compounds. This compound is of significant value for its role as a key intermediate in the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures with precise three-dimensional control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of β-lactam antibiotics and other active pharmaceutical ingredients (APIs) requiring a stereospecific β-lactam core.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the β-lactam structure imparts specific biological activity.
• Fine Chemical Building Block: Serves as a versatile precursor in custom synthesis and contract manufacturing for specialty chemicals.
• Academic & Industrial Research: Employed in medicinal chemistry programs for drug discovery, particularly in exploring new mechanisms of action involving β-lactam scaffolds.
• Peptidomimetic Development: Useful in the design and synthesis of peptidomimetics and protease inhibitors due to its constrained ring structure and functional handles.

Basic Information

Product Name	2-Oxetanone,3-Amino-4-Methyl-,(3S-Trans)-(9Ci)
CAS No.	131232-74-1
Molecular Formula	C4H7NO2
Molecular Weight	101.10 g/mol
Synonyms	(3S,4R)-3-Amino-4-methylazetidin-2-one; (3S,4R)-3-Amino-4-methyl-2-azetidinone; 3-Amino-4-methyl-2-oxetanone, (3S-trans)-; 4-Methyl-3-amino-2-azetidinone; trans-3-Amino-4-methyl-β-lactam; (3S,4R)-3-Amino-4-methyl-β-lactam; β-Lactam, 3-amino-4-methyl-, (3S,4R)-
EINECS	Contact for details

Quality Control

Our 2-Oxetanone,3-Amino-4-Methyl-,(3S-Trans)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.