Description

3-((2-Amino-3-Methyl-1-Oxopentyl)Amino)-1-(6-Amino-9H-Purin-9-Yl)-1,3-Dideoxy- β-D-Ribofuranuronic Acid is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
• Antiviral Drug Research: Used in the development of experimental antiviral compounds, particularly for RNA viruses.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in studies of enzyme mechanisms, nucleic acid metabolism, and cellular signaling pathways.
• Pro-drug Synthesis: Utilized in the design and synthesis of pro-drug formulations to enhance bioavailability and targeting.
• Labeled Compound Production: A starting material for synthesizing isotopically labeled (e.g., C13, N15) compounds for pharmacokinetic and metabolic studies.

Basic Information

Item	Details
Product Name	3-((2-Amino-3-Methyl-1-Oxopentyl)Amino)-1-(6-Amino-9H-Purin-9-Yl)-1,3-Dideoxy- β-D-Ribofuranuronic Acid
CAS No.	131206-83-2
Molecular Formula	C16H23N7O5
Molecular Weight	393.40 g/mol
Synonyms	N-(2-Amino-3-methyl-1-oxopentyl)-9H-purin-6-amine, 1-(6-Amino-9H-purin-9-yl)-1,3-dideoxy-3-[[(2S)-2-amino-3-methyl-1-oxopentyl]amino]-β-D-ribofuranuronic acid; 3-((2-Amino-3-methyl-1-oxopentyl)amino)-1-(6-aminopurin-9-yl)-1,3-dideoxy-β-D-ribofuranuronic acid; Nucleoside Derivative Intermediate; L-Isoleucine, N-[1-(6-amino-9H-purin-9-yl)-1,3-dideoxy-β-D-ribofuranuron-3-yl]-
EINECS	Contact for details

Quality Control

Our 3-((2-Amino-3-Methyl-1-Oxopentyl)Amino)-1-(6-Amino-9H-Purin-9-Yl)-1,3-Dideoxy- β-D-Ribofuranuronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.