Description

3-Hydroxy-7-(Hydroxyimino)Cholanic Acid is a high-purity, modified bile acid derivative that serves as a critical intermediate in advanced pharmaceutical synthesis. Its unique structure, featuring both hydroxy and hydroxyimino functional groups, makes it a valuable building block for the development of novel therapeutic agents and diagnostic compounds. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of liver-targeted drugs, metabolic regulators, and specialized biochemical probes.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel hepatoprotective agents and bile acid receptor modulators.
• Biochemical Research: Used as a reference standard and probe in studies of bile acid metabolism, transport, and signaling pathways.
• Diagnostic Agent Development: Serves as a core structure for creating contrast agents or tracers for liver and gallbladder imaging.
• Metabolic Pathway Studies: Employed in academic and industrial research to investigate enzymatic transformations related to cholesterol and bile acid synthesis.
• Chemical Synthesis: A versatile chiral building block for the synthesis of complex steroidal molecules with potential biological activity.

Basic Information

Product Name	3-Hydroxy-7-(Hydroxyimino)Cholanic Acid
CAS No.	131204-64-3
Molecular Formula	C₂₄H₃₉NO₄
Molecular Weight	405.58 g/mol
Synonyms	7-(Hydroxyimino)-3-hydroxycholan-24-oic Acid; 3α-Hydroxy-7-oximino-5β-cholan-24-oic Acid; 7-Oximino-3α-hydroxy-5β-cholanic Acid; 3-Hydroxy-7-oximinolithocholic Acid; 7-(Hydroxyimino)lithocholic Acid; 7-Oximinolithocholic Acid; Modified Bile Acid Derivative; Cholan-24-oic acid, 3-hydroxy-7-(hydroxyimino)-, (3α,5β)-
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-7-(Hydroxyimino)Cholanic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical development. We adhere to current Good Manufacturing Practices (cGMP) where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced chromatographic methods. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.