Description

Cornuside is a bioactive iridoid glycoside compound isolated from the genus *Cornus*, known for its significant pharmacological potential. This high-purity reference standard is essential for research and development in the nutraceutical and pharmaceutical sectors, where precise chemical identity and activity are paramount. It serves as a critical analytical standard for quality control in the production of botanical extracts and as a key intermediate in advanced therapeutic studies. Industries focused on natural product research, phytopharmaceutical development, and analytical chemistry rely on consistent, high-quality Cornuside to ensure product efficacy and regulatory compliance.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of herbal medicines and extracts containing *Cornus* species.
• Nutraceutical Ingredient R&D: Serves as a key bioactive marker compound in the development and standardization of dietary supplements aimed at supporting metabolic and inflammatory health.
• Academic & Clinical Research: Employed in *in vitro* and *in vivo* studies to investigate its potential anti-diabetic, anti-inflammatory, neuroprotective, and hepatoprotective properties.
• Botanical Extract Quality Control: Acts as a quantitative marker in HPLC and LC-MS methods to ensure the potency, authenticity, and batch-to-batch consistency of commercial *Cornus officinalis* (Cornelian cherry) extracts.
• Cosmeceutical Formulations: Investigated for inclusion in advanced skincare products due to its reported antioxidant and anti-aging biological activities.
• Chemical Synthesis Intermediate: Utilized as a starting material or building block for the semi-synthesis of novel iridoid derivatives with enhanced bioactivity.

Basic Information

Product Name	Cornuside
CAS No.	131189-57-6
Molecular Formula	C24H30O14
Molecular Weight	542.49 g/mol
Synonyms	Cornuside; 8-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)chromen-4-one; 7-O-Methylmorroniside; Loganic acid 7-methyl ester; (1S,4aS,7S,7aS)-1-(β-D-Glucopyranosyloxy)-7-(methoxycarbonyl)-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid methyl ester; Corni Fructus glycoside
EINECS	Contact for details

Quality Control

Our Cornuside is manufactured under strict quality management systems to ensure it meets the high standards required for research and development. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (IR, NMR, MS) for structural confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting batch-specific results for identity, purity, and impurities. Our quality commitment aligns with the needs of industries requiring traceable and reliable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.