Description

(R)-A,A-Bis(3,5-Dichlorophenyl)-2-Pyrrolidinemethanol Hydrochloride is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its role as a key building block for the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical control. This compound is essential for research institutions and manufacturers engaged in the development of novel drugs, agrochemicals, and other fine chemicals where the (R)-enantiomer is the desired active form.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in catalytic asymmetric reactions.
• Medicinal Chemistry R&D: A valuable compound for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring specific stereochemistry.

Basic Information

Product Name	(R)-A,A-Bis(3,5-Dichlorophenyl)-2-Pyrrolidinemethanol Hydrochloride
CAS No.	131180-61-5
Molecular Formula	C17H15Cl4NO • HCl
Molecular Weight	423.13 g/mol (Free base: 387.12 g/mol)
Synonyms	(R)-α,α-Bis(3,5-dichlorophenyl)-2-pyrrolidinemethanol hydrochloride; (R)-2-Pyrrolidinemethanol, α,α-bis(3,5-dichlorophenyl)-, hydrochloride; (R)-Bis(3,5-dichlorophenyl)(2-pyrrolidinyl)methanol hydrochloride; (R)-BDPM Hydrochloride; (R)-Enantiomer of A,A-Bis(3,5-dichlorophenyl)-2-pyrrolidinemethanol HCl
EINECS	Contact for details

Quality Control

Our (R)-A,A-Bis(3,5-Dichlorophenyl)-2-Pyrrolidinemethanol Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including Chiral HPLC for enantiomeric excess verification and standard pharmacopeial identification tests. A detailed Certificate of Analysis (COA) is supplied with each batch, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.