Description

3,3,3-Trifluoro-2-Methyl-n-[4-Nitro-3-(Trifluoromethyl)Phenyl]Propanamide is a specialized fluorinated aromatic amide building block of significant interest in advanced organic synthesis. Its unique structure, featuring multiple trifluoromethyl and nitro groups, makes it a valuable intermediate for creating novel compounds with tailored electronic and steric properties. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, stability, and lipophilicity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated aromatic units.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, amide bond formations, and as a scaffold for constructing complex, multi-functional molecules in medicinal chemistry.
• Dye & Pigment Intermediate: Acts as a precursor for synthesizing specialized dyes and pigments where nitro and trifluoromethyl groups modify color properties and lightfastness.

Basic Information

Product Name	3,3,3-Trifluoro-2-Methyl-n-[4-Nitro-3-(Trifluoromethyl)Phenyl]Propanamide
CAS No.	131131-33-4
Molecular Formula	C12H8F6N2O3
Molecular Weight	342.20 g/mol
Synonyms	N-[4-Nitro-3-(trifluoromethyl)phenyl]-3,3,3-trifluoro-2-methylpropanamide; 3,3,3-Trifluoro-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide; 2-Methyl-3,3,3-trifluoro-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide; Propanamide, 3,3,3-trifluoro-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-; CAS 131131-33-4
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-2-Methyl-n-[4-Nitro-3-(Trifluoromethyl)Phenyl]Propanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.