Description

Boc-L-Tyr(Po3H2)-Oh 2Dipea is a protected, phosphorylated derivative of the amino acid L-tyrosine, specifically designed for advanced peptide synthesis and biochemical research. This compound is critical for introducing phosphotyrosine mimetics into peptide chains, enabling the study of phosphorylation-dependent signaling pathways and protein-protein interactions. It is an essential building block for pharmaceutical researchers, medicinal chemists, and biochemists working in drug discovery, proteomics, and the development of kinase inhibitors.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of phosphopeptides and their analogs.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of therapeutics targeting tyrosine kinase pathways, such as in oncology.
• Biochemical Research: Serves as a crucial reagent for studying protein phosphorylation, enzyme kinetics, and signal transduction mechanisms.
• Proteomics & Biomarker Development: Employed in the synthesis of standardized peptides for mass spectrometry calibration and antibody production.
• Pharmaceutical Intermediates: Acts as a high-purity intermediate in the synthesis of complex active pharmaceutical ingredients (APIs).
• Academic Research: A fundamental tool in university and institutional labs for investigating cell signaling and post-translational modifications.

Basic Information

Product Name	Boc-L-Tyr(Po3H2)-Oh 2Dipea
CAS No.	131124-82-8
Molecular Formula	C₁₈H₂₉N₂O₉P • 2(C₈H₁₉N)
Molecular Weight	Contact for details
Synonyms	Boc-O-phospho-L-tyrosine dicyclohexylammonium salt; Boc-L-phosphotyrosine(DCHA)₂; N-tert-Butoxycarbonyl-O-phosphono-L-tyrosine bis(dicyclohexylamine) salt; Boc-Tyr(PO₃H₂)-OH • 2 DCHA; (2S)-3-(4-Phosphonophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid bis(dicyclohexylamine) salt; Boc-P-Tyr-OH • 2 DCHA; Protected Phosphotyrosine; Boc-L-Tyr(PO₃H₂)-OH DCHA salt
EINECS	Contact for details

Quality Control

Our Boc-L-Tyr(Po3H2)-Oh 2Dipea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications to ensure consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.