Description

Methyl (R)-2-(Benzylamino)-3-Hydroxypropanoate CAS NO 131110-76-4 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. This compound is valued for its role in constructing complex molecules with defined stereochemistry, which is critical for biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), fine chemicals, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in β-amino acid and peptide mimetic research.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for metal-catalyzed reactions requiring high enantioselectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological development for organic and medicinal chemistry.
• Peptidomimetic Scaffold Construction: Integral for creating modified peptide structures with enhanced stability or specific receptor binding profiles.

Basic Information

Product Name	Methyl (R)-2-(Benzylamino)-3-Hydroxypropanoate
CAS No.	131110-76-4
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(R)-Methyl 2-(Benzylamino)-3-hydroxypropanoate; Methyl D-2-(Benzylamino)-3-hydroxypropionate; (R)-2-(Benzylamino)-3-hydroxypropionic acid methyl ester; (R)-2-Benzylamino-3-hydroxypropionic acid methyl ester; D-2-Benzylamino-3-hydroxypropionic acid methyl ester; (R)-HomoSer(OBzl)-OMe; Methyl (R)-2-amino-3-hydroxy-3-phenylpropanoate (benzylamine adduct)
EINECS	Contact for details

Quality Control

Our production of Methyl (R)-2-(Benzylamino)-3-Hydroxypropanoate adheres to stringent in-process controls to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized and meets rigorous internal specifications. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.